We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
Most Useful Reviews
9
Positive effect
The composition is good, and I bought it chiefly for its effectiveness. I have enjoyed sound sleep without leg cramps and a notable absence of fatigue, which re-emerged when I temporarily stopped taking it. Resuming led to a surprisingly cheerful mood the following day.
Read More
9
Calmer and relaxed
I am thrilled with this product! Having suffered from chronic stress and insomnia, my doctor recommended magnesium. This powder mixes well and has a pleasant lemon taste. Within a few days, I felt calmer, slept better, and even found relief from muscle aches after workouts. Highly recommend for anyone looking to improve their overall health and mood!
Read More
7.5
Well absorbed
This magnesium chelate is excellently absorbed and does not irritate the stomach. Although the taste is not very pleasing, its efficacy in alleviating fatigue is swift, benefiting muscle function and nervous system health.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.2
All Reviews
Positive Reviews
Negative Reviews
9
Positive effect
The composition is good, and I bought it chiefly for its effectiveness. I have enjoyed sound sleep without leg cramps and a notable absence of fatigue, which re-emerged when I temporarily stopped taking it. Resuming led to a surprisingly cheerful mood the following day.
Read More
9
Calmer and relaxed
I am thrilled with this product! Having suffered from chronic stress and insomnia, my doctor recommended magnesium. This powder mixes well and has a pleasant lemon taste. Within a few days, I felt calmer, slept better, and even found relief from muscle aches after workouts. Highly recommend for anyone looking to improve their overall health and mood!
Read More
7.5
Well absorbed
This magnesium chelate is excellently absorbed and does not irritate the stomach. Although the taste is not very pleasing, its efficacy in alleviating fatigue is swift, benefiting muscle function and nervous system health.
Read More
9
Energized daily
This product is excellent. With just 100mg a day, I feel invigorated and my chronic fatigue remains under control.
Read More
9
Post-exercise relief
I keep this product at home constantly. It has proven invaluable for relieving post-exercise fatigue and cramps, contributing positively to my recovery and overall nerves.
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.
The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
While there is ongoing research into the potential benefits of magnesium for various health conditions, including Chronic Fatigue Syndrome (CFS), definitive conclusions remain elusive. Magnesium plays a critical role in energy production, muscle function, and overall metabolism, which suggests it may provide some support for those suffering from CFS. Some anecdotal evidence and small-scale studies suggest that magnesium supplementation could help alleviate certain symptoms associated with fatigue, particularly if a deficiency is present. However, further extensive clinical studies are needed to establish a clear link between magnesium supplementation and improvement in CFS symptoms.
It's important for individuals considering magnesium supplementation to consult with a healthcare professional. They can determine individual needs and whether magnesium may be beneficial based on personal health profiles and existing conditions. Additionally, magnesium should not be viewed as a standalone solution for Chronic Fatigue Syndrome; a comprehensive approach that includes lifestyle changes, a balanced diet, and other treatments may be necessary for managing symptoms effectively.
Based on user reviews, individuals taking magnesium supplements for Chronic Fatigue Syndrome report varying timelines for experiencing positive results. Many users mention feeling improvements within a few days to a week. For instance, one reviewer noted clear benefits in terms of fatigue reduction and better sleep quality just after ten days of use (review ID: Read Review). Another reviewer, who highlighted mental and muscle fatigue relief, reported feeling a significant reduction in symptoms just after a few days (review ID: Read Review).
However, it’s essential to note that while some users found rapid results, others like a user who took the supplement for about a month indicated only slight improvements in muscle pain and fatigue, suggesting that results can vary significantly depending on the individual and their specific conditions (review ID: Read Review). It may take consistent usage over several weeks for optimal results, so patience and monitoring your response is advised.
The scientific research surrounding magnesium supplementation and its potential benefits for Chronic Fatigue Syndrome (CFS) presents a mixed but promising picture. Several studies suggest that magnesium might provide some improvements in symptoms for individuals suffering from this debilitating condition. For instance, a randomized trial found that patients receiving magnesium sulfate experienced notable enhancements in energy, emotional wellbeing, and pain relief compared to those receiving a placebo [5]. Additionally, some reviews have noted that while magnesium shows potential, the overall effectiveness remains uncertain due to the limitations of the studies, such as small sample sizes and biases [1].
Moreover, a case study reported significant improvements in one patient’s fatigue following weekly intravenous magnesium sulfate treatments, indicating that magnesium can lead to positive changes in some cases [3]. However, other investigations have pointed out that magnesium supplementation does not universally translate to significant benefits, as many patients did not experience a substantial decrease in fatigue levels, highlighting the need for more rigorous, sizable trials to establish definitive benefits [2]. In summary, while magnesium shows some promise in alleviating CFS symptoms for certain patients, further research is essential to fully understand its effectiveness.
Users have reported a range of improvements in symptoms after taking magnesium supplements, particularly for issues related to fatigue, sleep, and muscle discomfort. For instance, one user mentioned feeling calmer and experiencing better sleep quality within just a few days of using the product, along with relief from muscle aches post-workout (review ID: Read Review). Another reviewer highlighted a significant decrease in fatigue and the absence of leg cramps while taking magnesium, noting a cheerful mood the following day after resuming their regimen (review ID: Read Review).
Moreover, some users indicated longer-term benefits, with one reviewer noting increased energy levels and reduced headaches after ten days of daily use (review ID: Read Review). However, results can vary significantly among individuals. Some users reported only slight improvements in their muscle pain and fatigue after a month of use, expressing disappointment with the taste of the powder form (review ID: Read Review). Overall, while many have found magnesium beneficial for managing fatigue and improving sleep, individual experiences may differ, underscoring the importance of monitoring one’s response to the supplement.
Users have reported various experiences when combining magnesium supplements with other products to address Chronic Fatigue Syndrome. Many individuals noted a positive impact when taking magnesium alongside additional supplements such as vitamin D3+K2 and vitamin B6. For instance, one user shared that after ten days of this combination, they saw a significant boost in energy levels and reduced headaches, highlighting the synergistic effects of these nutrients on their overall well-being (Read Review). Another user found that magnesium enhanced their recovery post-exercise, suggesting that users may benefit from pairing magnesium with supplements tailored for physical recovery (Read Review).
Conversely, some users expressed mixed feelings about the combination of magnesium with other supplements. For instance, while one reviewer indicated magnesium was effective for their fatigue, they found the taste of the powder form quite challenging and opted to switch to capsules for better convenience (Read Review). Others experienced only slight improvements despite combining magnesium with rigorous supplementation, emphasizing the importance of individual responses to different combinations in managing fatigue-related symptoms (Read Review). Overall, combining magnesium with complementary supplements may provide benefits, but users should be aware of individual variations in response.
Users report a range of experiences with magnesium as a treatment for Chronic Fatigue Syndrome, particularly regarding the effective dosing. A common theme is that lower doses, around 100mg per day, can lead to noticeable improvements in energy levels and overall well-being. One user advises that with just 100mg daily, their chronic fatigue remains under control, indicating that lower doses might be effective for many (Read Review). Other users echoed a similar sentiment, noticing significant boosts in energy levels when taking suitable doses, whether in powder or capsule form.
Several users highlight the necessity of finding the right formulation that suits them without causing digestive discomfort. They reported great benefits with magnesium chelate, which is well-absorbed and generally gentle on the stomach. Doses that combine magnesium with other vitamins, like vitamin D3 and B6, seem to provide enhanced results in alleviating fatigue and improving mood (Read Review). The feedback suggests that while personal experiences vary, starting with lower doses of magnesium could be beneficial for managing fatigue, potentially increasing as needed based on individual tolerance and effects.
7.5
Increased energy
Very pleased with the fast delivery and high-quality packaging. There were no damages, and the dosage is excellent, made from natural herbal ingredients. The capsules are a tad large, but swallowing is easy, and they taste of citrus. I take one capsule daily with meals, accompanied by vitamin D3+K2, magnesium, and vitamin B6. After ten days of use, I’ve noticed a significant boost in my energy levels; previous headaches and fatigue have subsided, and my mood remains elevated. I highly recommend it, especially for those interested in sports or following a diet, as omega-3 rejuvenates the body effectively.
9
Calmer and relaxed
I am thrilled with this product! Having suffered from chronic stress and insomnia, my doctor recommended magnesium. This powder mixes well and has a pleasant lemon taste. Within a few days, I felt calmer, slept better, and even found relief from muscle aches after workouts. Highly recommend for anyone looking to improve their overall health and mood!
6
Muscle pain relief
I bought this magnesium to alleviate muscle aches and fatigue. After a month, I’ve noticed slight improvements in muscle pain as I increased my workouts, but the taste of this powder mixed in water is horrid. I will probably opt for pills next time, as the flavour is difficult to mask.
9
Positive effect
The composition is good, and I bought it chiefly for its effectiveness. I have enjoyed sound sleep without leg cramps and a notable absence of fatigue, which re-emerged when I temporarily stopped taking it. Resuming led to a surprisingly cheerful mood the following day.
9
Post-exercise relief
I keep this product at home constantly. It has proven invaluable for relieving post-exercise fatigue and cramps, contributing positively to my recovery and overall nerves.
7.5
Quality issue
This magnesium works effectively, but the flavour is a challenge to endure. I’m switching to capsules for convenience. It seems beneficial for my fatigue at this point.
9
Energized daily
This product is excellent. With just 100mg a day, I feel invigorated and my chronic fatigue remains under control.
8
Magnesium potentially benefits CFS patients
Red blood cell magnesium and chronic fatigue syndrome.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
References
Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. 10.1186/1472-6882-11-87
Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.